Rapid Onset of Retinal Toxicity From High-Dose Hydroxychloroquine Given for Cancer Therapy.
Identifieur interne : 000E74 ( Main/Exploration ); précédent : 000E73; suivant : 000E75Rapid Onset of Retinal Toxicity From High-Dose Hydroxychloroquine Given for Cancer Therapy.
Auteurs : Loh-Shan B. Leung [États-Unis] ; Joel W. Neal [États-Unis] ; Heather A. Wakelee [États-Unis] ; Lecia V. Sequist [États-Unis] ; Michael F. Marmor [États-Unis]Source :
- American journal of ophthalmology [ 1879-1891 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Angiographie fluorescéinique, Antinéoplasiques (usage thérapeutique), Antirhumatismaux (administration et posologie), Antirhumatismaux (effets indésirables), Association de médicaments, Carcinome pulmonaire non à petites cellules (traitement médicamenteux), Champs visuels, Chlorhydrate d'erlotinib (usage thérapeutique), Femelle, Humains, Hydroxychloroquine (administration et posologie), Hydroxychloroquine (effets indésirables), Mâle, Rétine (), Rétine (anatomopathologie), Rétinopathies (), Rétinopathies (diagnostic), Sujet âgé, Tests du champ visuel, Tomographie par cohérence optique, Tumeurs du poumon (traitement médicamenteux), Électrorétinographie, Études rétrospectives.
- MESH :
- administration et posologie : Antirhumatismaux, Hydroxychloroquine.
- anatomopathologie : Rétine.
- diagnostic : Rétinopathies.
- effets indésirables : Antirhumatismaux, Hydroxychloroquine.
- traitement médicamenteux : Carcinome pulmonaire non à petites cellules, Tumeurs du poumon.
- usage thérapeutique : Antinéoplasiques, Chlorhydrate d'erlotinib.
- Adulte d'âge moyen, Angiographie fluorescéinique, Association de médicaments, Champs visuels, Femelle, Humains, Mâle, Rétine, Rétinopathies, Sujet âgé, Tests du champ visuel, Tomographie par cohérence optique, Électrorétinographie, Études rétrospectives.
English descriptors
- KwdEn :
- Aged, Antineoplastic Agents (therapeutic use), Antirheumatic Agents (administration & dosage), Antirheumatic Agents (adverse effects), Carcinoma, Non-Small-Cell Lung (drug therapy), Drug Therapy, Combination, Electroretinography, Erlotinib Hydrochloride (therapeutic use), Female, Fluorescein Angiography, Humans, Hydroxychloroquine (administration & dosage), Hydroxychloroquine (adverse effects), Lung Neoplasms (drug therapy), Male, Middle Aged, Retina (drug effects), Retina (pathology), Retinal Diseases (chemically induced), Retinal Diseases (diagnosis), Retrospective Studies, Tomography, Optical Coherence, Visual Field Tests, Visual Fields.
- MESH :
- chemical , administration & dosage : Antirheumatic Agents, Hydroxychloroquine.
- chemical , adverse effects : Antirheumatic Agents, Hydroxychloroquine.
- chemical , therapeutic use : Antineoplastic Agents, Erlotinib Hydrochloride.
- chemically induced : Retinal Diseases.
- diagnosis : Retinal Diseases.
- drug effects : Retina.
- drug therapy : Carcinoma, Non-Small-Cell Lung, Lung Neoplasms.
- pathology : Retina.
- Aged, Drug Therapy, Combination, Electroretinography, Female, Fluorescein Angiography, Humans, Male, Middle Aged, Retrospective Studies, Tomography, Optical Coherence, Visual Field Tests, Visual Fields.
Abstract
To report rapid onset of retinal toxicity in a series of patients followed on high-dose (1000 mg daily) hydroxychloroquine during an oncologic clinical trial studying hydroxychloroquine with erlotinib for non-small cell lung cancer.
DOI: 10.1016/j.ajo.2015.07.012
PubMed: 26189086
Affiliations:
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Le document en format XML
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<term>Antinéoplasiques (usage thérapeutique)</term>
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<term>Électrorétinographie</term>
<term>Études rétrospectives</term>
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<front><div type="abstract" xml:lang="en">To report rapid onset of retinal toxicity in a series of patients followed on high-dose (1000 mg daily) hydroxychloroquine during an oncologic clinical trial studying hydroxychloroquine with erlotinib for non-small cell lung cancer.</div>
</front>
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<name sortKey="Marmor, Michael F" sort="Marmor, Michael F" uniqKey="Marmor M" first="Michael F" last="Marmor">Michael F. Marmor</name>
<name sortKey="Neal, Joel W" sort="Neal, Joel W" uniqKey="Neal J" first="Joel W" last="Neal">Joel W. Neal</name>
<name sortKey="Sequist, Lecia V" sort="Sequist, Lecia V" uniqKey="Sequist L" first="Lecia V" last="Sequist">Lecia V. Sequist</name>
<name sortKey="Wakelee, Heather A" sort="Wakelee, Heather A" uniqKey="Wakelee H" first="Heather A" last="Wakelee">Heather A. Wakelee</name>
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